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An Innovative Method to Classify SERMs Based on the Dynamics of Estrogen Receptor Transcriptional Activity in Living Animals

Using a mouse model engineered to measure estrogen receptor (ER) transcriptional activity in living organisms, we investigated the effect of long-term (21 d) hormone replacement on ER signaling by whole-body in vivo imaging. Estrogens and selective ER modulators were administered daily at doses equi...

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Bibliografiske detaljer
Main Authors: Rando, Gianpaolo, Horner, David, Biserni, Andrea, Ramachandran, Balaji, Caruso, Donatella, Ciana, Paolo, Komm, Barry, Maggi, Adriana
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852355/
https://ncbi.nlm.nih.gov/pubmed/20197311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0514
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