Estradiol-Induced Object Memory Consolidation in Middle-Aged Female Mice Requires Dorsal Hippocampal Extracellular Signal-Regulated Kinase and Phosphatidylinositol 3-Kinase Activation

We previously demonstrated that dorsal hippocampal extracellular signal-regulated kinase (ERK) activation is necessary for 17β-estradiol (E(2)) to enhance novel object recognition in young ovariectomized mice (Fernandez et al., 2008). Here, we asked whether E(2) has similar memory-enhancing effects...

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Detalhes bibliográficos
Main Authors: Fan, Lu, Zhao, Zaorui, Orr, Patrick T., Chambers, Cassie H., Lewis, Michael C., Frick, Karyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852263/
https://ncbi.nlm.nih.gov/pubmed/20335475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4333-09.2010
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