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CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data

Motivation: DNA copy number aberration (CNA) is a hallmark of genomic abnormality in tumor cells. Recurrent CNA (RCNA) occurs in multiple cancer samples across the same chromosomal region and has greater implication in tumorigenesis. Current commonly used methods for RCNA identification require CNA...

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Detalhes bibliográficos
Main Authors: Zhang, Qunyuan, Ding, Li, Larson, David E., Koboldt, Daniel C., McLellan, Michael D., Chen, Ken, Shi, Xiaoqi, Kraja, Aldi, Mardis, Elaine R., Wilson, Richard K., Borecki, Ingrid B., Province, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852218/
https://ncbi.nlm.nih.gov/pubmed/20031968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp708
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