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Synthesis of Benzisoxazoles by the [3 + 2] Cycloaddition of in situ Generated Nitrile Oxides and Arynes

[Image: see text] A variety of substituted benzisoxazoles has been prepared by the [3 + 2] cycloaddition of nitrile oxides and arynes. Both components, being highly reactive intermediates, have been generated in situ by fluoride anion from readily prepared aryne precursors and chlorooximes. The reac...

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Hlavní autoři: Dubrovskiy, Anton V., Larock, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852127/
https://ncbi.nlm.nih.gov/pubmed/20184347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902921s
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