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Nitric oxide production and nitric oxide synthase type 2 expression by cotton rat (Sigmodon hispidus) macrophages reflect the same pattern as human macrophages

Our knowledge of the antibacterial role of nitric oxide (NO) during infection is based on studies of murine macrophages, which secrete large amounts of NO. In contrast, human macrophages produce very little NO and its relevance as an antibacterial mediator during infection of humans is uncertain. We...

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Hlavní autoři: Carsillo, Mary, Kutala, Vijay Kumar, Puschel, Karen, Blanco, Jorge, Kuppusamy, Periannan, Niewiesk, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852107/
https://ncbi.nlm.nih.gov/pubmed/19154756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2008.12.004
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