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Design and Optimization of Diclofenac Sodium Controlled Release Solid Dispersions by Response Surface Methodology
A 3(2) factorial design was employed to produce controlled release solid dispersions of diclofenac sodium in Eudragit RS and RL by coevaporation of their ethanol solution in a flash evaporator. The effect of critical formulation variables namely total polymer pay loads and levels of Eudragit RL on p...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Medknow Publications
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852056/ https://ncbi.nlm.nih.gov/pubmed/20390076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.40327 |
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