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“Control” laboratory rodents are metabolically morbid: Why it matters

Failure to recognize that many standard control rats and mice used in biomedical research are sedentary, obese, glucose intolerant, and on a trajectory to premature death may confound data interpretation and outcomes of human studies. Fundamental aspects of cellular physiology, vulnerability to oxid...

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Bibliografske podrobnosti
Main Authors: Martin, Bronwen, Ji, Sunggoan, Maudsley, Stuart, Mattson, Mark P.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852022/
https://ncbi.nlm.nih.gov/pubmed/20194732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912955107
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