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Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli

Bacillithiol (BSH), the α-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid, is a major low-molecular-weight thiol in Bacillus subtilis and related bacteria. Here, we identify genes required for BSH biosynthesis and provide evidence that the synthetic pathway has similarities to that...

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Autors principals: Gaballa, Ahmed, Newton, Gerald L., Antelmann, Haike, Parsonage, Derek, Upton, Heather, Rawat, Mamta, Claiborne, Al, Fahey, Robert C., Helmann, John D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851989/
https://ncbi.nlm.nih.gov/pubmed/20308541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000928107
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