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P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
The pathway involving the tumor suppressor gene TP53 can regulate tumor angiogenesis by unclear mechanisms. Here we show that p53 regulates hypoxic signaling through the transcriptional regulation of microRNA-107 (miR-107). We found that miR-107 is a microRNA expressed by human colon cancer specimen...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851979/ https://ncbi.nlm.nih.gov/pubmed/20308559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911082107 |
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