Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

Our previous analyses showed that allopregnanolone (APα) significantly increased proliferation of rodent and human neural progenitor cells in vitro. In this study, we investigated the efficacy of APα to promote neurogenesis in the hippocampal subgranular zone (SGZ), to reverse learning and memory de...

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Bibliografiske detaljer
Main Authors: Wang, Jun Ming, Singh, Chanpreet, Liu, Lifei, Irwin, Ronald W., Chen, Shuhua, Chung, Eun Ji, Thompson, Richard F., Brinton, Roberta Diaz
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851948/
https://ncbi.nlm.nih.gov/pubmed/20231471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001422107
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