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Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

Yeast members of the ORMDL family of endoplasmic reticulum (ER) membrane proteins play a central role in lipid homeostasis and protein quality control. In the absence of yeast Orm1 and Orm2, accumulation of long chain base, a sphingolipid precursor, suggests dysregulation of sphingolipid synthesis....

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Detalles Bibliográficos
Main Authors: Han, Sumin, Lone, Museer A., Schneiter, Roger, Chang, Amy
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851911/
https://ncbi.nlm.nih.gov/pubmed/20212121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911617107
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