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Enhancing DNA vaccine potency by co-administration of xenogenic MHC-class-I DNA
Intramuscular administration of DNA vaccines can lead to the generation of antigen-specific immune responses through cross-priming mechanisms. We propose a strategy that is capable of leading to local inflammation and enhancing cross-priming, thus resulting in improved antigen-specific immune respon...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851845/ https://ncbi.nlm.nih.gov/pubmed/19940864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.152 |
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