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Physicochemical property distributions for accurate and rapid pairwise protein homology detection

BACKGROUND: The challenge of remote homology detection is that many evolutionarily related sequences have very little similarity at the amino acid level. Kernel-based discriminative methods, such as support vector machines (SVMs), that use vector representations of sequences derived from sequence pr...

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Detalhes bibliográficos
Main Authors: Webb-Robertson, Bobbie-Jo M, Ratuiste, Kyle G, Oehmen, Christopher S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851606/
https://ncbi.nlm.nih.gov/pubmed/20302613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-145
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