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Temperature dependence of the flexibility of thermophilic and mesophilic flavoenzymes of the nitroreductase fold

A widely held hypothesis regarding the thermostability of thermophilic proteins states asserts that, at any given temperature, thermophilic proteins are more rigid than their mesophilic counterparts. Many experimental and computational studies have addressed this question with conflicting results. H...

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Autors principals: Merkley, Eric D., Parson, William W., Daggett, Valerie
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851445/
https://ncbi.nlm.nih.gov/pubmed/20083491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp090
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