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Kinetic and Structural Analysis of Substrate Specificity in Two Copper Amine Oxidases from Hansenula polymorpha,

The structural underpinnings of enzyme substrate specificity are investigated in a pair of copper amine oxidases (CAOs) from Hansenula polymorpha (HPAO-1 and HPAO-2). The X-ray crystal structure (to 2.0 Å resolution) and steady state kinetic data of the second copper amine oxidase (HPAO-2) are prese...

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Bibliografiske detaljer
Main Authors: Chang, Cindy M., Klema, Valerie J., Johnson, Bryan J., Mure, Minae, Klinman, Judith P., Wilmot, Carrie M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851405/
https://ncbi.nlm.nih.gov/pubmed/20155950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901933d
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