Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F

Human cytidine deaminases, including APOBEC3G (A3G) and A3F, are part of a cellular defense system against retroviruses and retroelements including non-LTR retrotransposons LINE-1 (L1) and Alu. Expression of cellular A3 proteins is sufficient for inhibition of L1 and Alu retrotransposition, but the...

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Bibliographic Details
Main Authors: Khatua, Atanu K., Taylor, Harry E., Hildreth, James E. K., Popik, Waldemar
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851184/
https://ncbi.nlm.nih.gov/pubmed/20153011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.01.021
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