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Inhibitory Effects and Metabolism of 5-Fluoropyrimidine Derivatives in Pneumococcus

5-Fluorouracil (FU), 5-fluorocytosine, and the riboside and deoxyriboside derivatives of these fluoropyrimidines each exhibit a different spectrum of inhibitory effects in pneumococci. The biochemical basis of this finding seems to be the extremely low level of nucleoside phosphorylase (hydrolase) a...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Autores principales: Bean, Barry, Tomasz, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1971
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC285111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4396791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.106.2.412-420.1971
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