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High Dihydrofolate Reductase Levels in Diplococcus pneumoniae After Mutation in the Structural Gene: Biochemical and Immunological Evidence for Increased Synthesis
A unique class of missense mutations in the dihydrofolate reductase structural gene of Diplococcus pneumoniae determines marked increases in the corresponding enzyme activity. Immunological evidence, based on precipitating and neutralizing antibody reactions, is presented in support of previously de...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC285099/ https://ncbi.nlm.nih.gov/pubmed/4396789 |
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