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Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection

IL-17 is proinflammatory cytokine secreted by a unique CD4+ T (Th(17)) cell subset and proposed to play a role in host defense. We hypothesized that Th(17) cells are lost in HIV-1 infection. HIV-1-infected children with plasma viremia below 50 copies/ml had IL-17 production, whereas those with detec...

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Detalhes bibliográficos
Main Authors: Ndhlovu, Lishomwa C., Chapman, Joan M., Jha, Aashish R., Snyder-Cappione, Jennifer E., Pagán, Moraima, Leal, Fabio E., Boland, Brigid S., Norris, Philip J., Rosenberg, Michael G., Nixon, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850608/
https://ncbi.nlm.nih.gov/pubmed/18453860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3282ff884e
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