Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

Plaque rupture underlies most myocardial infarctions. Plaques vulnerable to rupture have thin fibrous caps, an excess of macrophages over vascular smooth muscle cells, large lipid cores, and depletion of collagen and other matrix proteins form the cap and lipid core. Production of matrix metalloprot...

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Bibliographic Details
Main Authors: Newby, Andrew C., George, Sarah J., Ismail, Yasmin, Johnson, Jason L., Sala-Newby, Graciela B., Thomas, Anita C.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850555/
https://ncbi.nlm.nih.gov/pubmed/19492140
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