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Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms

The aim of this study was to investigate chitosan/siRNA complexes formulated with various chitosan salts (CS) including chitosan aspartate (CS-Asp), chitosan glutamate (CS-Glu), chitosan acetate (CS-Ac), and chitosan hydrochloride (CS-HCl) for in vitro siRNA delivery into stable and constitutive enh...

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Detalhes bibliográficos
Main Authors: Techaarpornkul, Sunee, Wongkupasert, Sirirat, Opanasopit, Praneet, Apirakaramwong, Auayporn, Nunthanid, Jurairat, Ruktanonchai, Uracha
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850492/
https://ncbi.nlm.nih.gov/pubmed/20058108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9355-6
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