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In Vitro and In Vivo Evaluation of Proniosomes Containing Celecoxib for Oral Administration
The objectives of this research were to prepare celecoxib proniosomes and evaluate the influence of proniosomal formulation on the oral bioavailability of the drug in human volunteers. A new proniosomal delivery system for a poorly water-soluble drug such as celecoxib was developed and subjected to...
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Format: | Artigo |
Jezik: | Inglês |
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Springer US
2010
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850489/ https://ncbi.nlm.nih.gov/pubmed/20058106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9364-5 |
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