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In Vitro Release Kinetics and Bioavailability of Gastroretentive Cinnarizine Hydrochloride Tablet

An oral sustained release dosage form of cinnarizine HCl (CNZ) based on gastric floating matrix tablets was studied. The release of CNZ from different floating matrix formulations containing four viscosity grades of hydroxypropyl methylcellulose, sodium alginate or polyethylene oxide, and gas-formin...

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Autores principales: Nagarwal, Ramesh C., Ridhurkar, Devendra N., Pandit, J. K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850455/
https://ncbi.nlm.nih.gov/pubmed/20182827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9380-5
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