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Genistein potentiates activity of the cation channel TRPC5 independently of tyrosine kinases

BACKGROUND AND PURPOSE: TRPC5 is a Ca(2+)-permeable channel with multiple modes of activation. We have explored the effects of genistein, a plant-derived isoflavone, on TRPC5 activity, and the mechanism(s) involved. EXPERIMENTAL APPROACH: Effects of genistein on TRPC5 channels were investigated in T...

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Detalhes bibliográficos
Main Authors: Wong, Ching-On, Huang, Yu, Yao, Xiaoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850405/
https://ncbi.nlm.nih.gov/pubmed/20233211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00636.x
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