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mGluR-mediated and endocannabinoid-dependent long-term depression in the hilar region of the rat dentate gyrus

We report that bath application of the group I mGluR agonist (RS)-3,5-dihydroxyphenylglycine (DHPG) causes acute inhibition of evoked IPSCs recorded from hilar mossy cells, and that significant long-term depression (LTD) of synaptic transmission remains following washout of DHPG. Subsequent experime...

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Bibliografiske detaljer
Main Authors: Nahir, Ben, Lindsly, Casie, Frazier, Charles J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850117/
https://ncbi.nlm.nih.gov/pubmed/20045707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.12.022
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