Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine

We tested the novel hypothesis that endogenous adenosine (eADO) activates low-affinity A3 receptors in a model of neurogenic diarrhea in the guinea pig colon. Dimaprit activation of H2 receptors was used to trigger a cyclic coordinated response of contraction and Cl(−) secretion. Contraction-relaxat...

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Main Authors: Bozarov, Andrey, Wang, Yu-Zhong, Yu, Jun Ge, Wunderlich, Jacqueline, Hassanain, Hamdy H., Alhaj, Mazin, Cooke, Helen J., Grants, Iveta, Ren, Tianhua, Christofi, Fievos L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Neuroregulation and Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850084/
https://ncbi.nlm.nih.gov/pubmed/19808660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00295.2009
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