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Antigen Identification and Characterization of Lung Cancer Specific Monoclonal Antibodies Produced by mAb Proteomics

A mass spectrometric (MS)-based strategy for antigen (Ag) identification and characterization of globally produced monoclonal antibodies (mAbs) is described. Mice were immunized with a mixture of native glycoproteins, isolated from the pooled plasma of patients with non-small cell lung cancer (NSCLC...

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Bibliografiske detaljer
Main Authors: Wang, Dongdong, Hincapie, Marina, Guergova-Kuras, Mariana, Kadas, Janos, Takacs, Laszlo, Karger, Barry L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849899/
https://ncbi.nlm.nih.gov/pubmed/20146545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900997z
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