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Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-κB and LEF-1

Collagen I has been shown to promote epithelial-mesenchymal transition (EMT), a critical process of embryonic development and disease progression. However, little is known about the signaling mechanisms by which collagen I induces this cellular transformation. Here we show that collagen I causes ILK...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Medici, Damian, Nawshad, Ali
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849845/
https://ncbi.nlm.nih.gov/pubmed/20018240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2009.12.003
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