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Disruption of Bidirectional Oocyte-Cumulus Paracrine Signaling During In Vitro Maturation Reduces Subsequent Mouse Oocyte Developmental Competence

Oocyte-cumulus cell bidirectional communication is essential for normal development of the oocyte and cumulus cells (CCs) within the follicle. We showed recently that addition of recombinant growth differentiation factor 9 (GDF9), which signals through the SMAD2/3 pathway, during mouse oocyte in vit...

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Detalhes bibliográficos
Main Authors: Yeo, Christine X., Gilchrist, Robert B., Lane, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849833/
https://ncbi.nlm.nih.gov/pubmed/19144958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.073908
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