PEDF and IL-6 CONTROL PROSTATE NEUROENDOCRINE DIFFERENTIATION VIA FEED-FORWARD MECHANISM

Pigment epithelium-derived factor (PEDF) promotes differentiation and survival of neuronal cells and expands the adult neuronal stem cell niche. In the prostate, PEDF is suppressed by androgen, with unclear physiological consequences. Ectopic and endogenous PEDF cause neuroendocrine differentiation...

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Autors principals: Smith, Norm D., Schulze-Hoepfner, Frank Thilo, Veliceasa, Dorina, Filleur, Stephanie, Huang, Lijun, Huang, Xue-Mei, Volpert, Olga V.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849797/
https://ncbi.nlm.nih.gov/pubmed/18433784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2008.01.081
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