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A Novel WT1 Gene Mutation in a Three-Generation Family with Progressive Isolated Focal Segmental Glomerulosclerosis

Background and objectives: Wilms tumor-suppressor gene-1 (WT1) plays a key role in kidney development and function. WT1 mutations usually occur in exons 8 and 9 and are associated with Denys-Drash, or in intron 9 and are associated with Frasier syndrome. However, overlapping clinical and molecular f...

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Hlavní autoři: Benetti, Elisa, Caridi, Gianluca, Malaventura, Cristina, Dagnino, Monica, Leonardi, Emanuela, Artifoni, Lina, Ghiggeri, Gian Marco, Tosatto, Silvio C.E., Murer, Luisa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849688/
https://ncbi.nlm.nih.gov/pubmed/20150449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05670809
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