Evolutionary dynamics of the immunodominant repeats of the Plasmodium vivax malaria-vaccine candidate circumsporozoite protein (CSP)

The circumsporozoite protein (CSP) of Plasmodium vivax, a major target for malaria vaccine development, has immunodominant B-cell epitopes mapped to central nonapeptide repeat arrays. To determine whether rearrangements of repeat motifs during mitotic DNA replication of parasites create significant...

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Main Authors: Patil, Aarti, Orjuela-Sánchez, Pamela, da Silva-Nunes, Mônica, Ferreira, Marcelo U.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849667/
https://ncbi.nlm.nih.gov/pubmed/20097310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2010.01.006
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