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Bone marrow stromal cells increase oligodendrogenesis after stroke

Oligodendrocytes are sensitive to ischemic damage. The Sonic hedgehog (Shh) pathway is critical in oligodendrogenesis; Gli1 is the principal effector of Shh signaling. We investigated oligodendrogenesis and Shh/Gli1 pathway activation after bone marrow stromal cell (BMSC) treatment of stroke in rats...

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Autors principals: Zhang, Jing, Li, Yi, Zhang, Zheng Gang, Lu, Mei, Borneman, Jade, Buller, Ben, Savant-Bhonsale, Smita, Elias, Stanton B, Chopp, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849641/
https://ncbi.nlm.nih.gov/pubmed/19384336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.41
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