Mechanisms of Ganglioside Inhibition of APC Function

Gangliosides shed by tumor cells exert potent inhibitory effects on cellular immune responses. Here we have studied ganglioside inhibition of APC function. When human monocytes were preincubated in 50 µM highly purified ganglioside G(D1a), pulsed with tetanus toxoid (TT), and washed, the expected Ag...

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Hauptverfasser: Caldwell, Sheila, Heitger, Andreas, Shen, Weiping, Liu, Yihui, Taylor, Barbara, Ladisch, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849639/
https://ncbi.nlm.nih.gov/pubmed/12902465
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