E1A Interacts with Two Opposing Transcriptional Pathways To Induce Quiescent Cells into S Phase

Despite data suggesting that the adenovirus E1A protein of 243 amino acids creates an S-phase environment in quiescent cells by overcoming the nucleosomal repression of E2F-regulated genes, the precise mechanisms underlying E1A's ability in this process have not yet been defined at the biochemi...

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Bibliographic Details
Main Authors: Sha, Jingfeng, Ghosh, Mrinal K., Zhang, Keman, Harter, Marian L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849484/
https://ncbi.nlm.nih.gov/pubmed/20089639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02131-09
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