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Interaction of an Essential Escherichia coli GTPase, Der, with the 50S Ribosome via the KH-Like Domain

Der, an essential Escherichia coli tandem GTPase, has been implicated in 50S subunit biogenesis. The rrmJ gene encodes a methyltransferase that modifies the U2552 residue of 23S rRNA, and its deletion causes a severe growth defect. Peculiarly, overexpression of Der suppresses growth impairment. In t...

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Autori principali: Hwang, Jihwan, Inouye, Masayori
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849445/
https://ncbi.nlm.nih.gov/pubmed/20172997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00045-10
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