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Neutrophil Gelatinase-Associated Lipocalin Expresses Antimicrobial Activity by Interfering with l-Norepinephrine-Mediated Bacterial Iron Acquisition

l-norepinephrine (NE) is a neuroendocrine catecholamine that supports bacterial growth by mobilizing iron from a primary source such as holotransferrin to increase its bioavailability for cellular uptake. Iron complexes of NE resemble those of bacterial siderophores that are scavenged by human neutr...

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Detalles Bibliográficos
Main Authors: Miethke, Marcus, Skerra, Arne
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849382/
https://ncbi.nlm.nih.gov/pubmed/20086155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01158-09
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