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Proteus mirabilis pmrI, an RppA-Regulated Gene Necessary for Polymyxin B Resistance, Biofilm Formation, and Urothelial Cell Invasion

Proteus mirabilis is naturally resistant to polymyxin B (PB). To investigate the underlying mechanisms, Tn5 mutagenesis was performed, and a mutant exhibiting increased PB susceptibility was isolated. The mutant was found to have Tn5 inserted into the PpmrI (Proteus pmrI) gene, a gene which may enco...

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Hlavní autoři: Jiang, Sin-Sien, Liu, Ming-Che, Teng, Lee-Jene, Wang, Won-Bo, Hsueh, Po-Ren, Liaw, Shwu-Jen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849355/
https://ncbi.nlm.nih.gov/pubmed/20123999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01219-09
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