Optimization and Application of a Multiplex Bead-Based Assay To Quantify Serotype-Specific IgG against Streptococcus pneumoniae Polysaccharides: Response to the Booster Vaccine after Immunization with the Pneumococcal 7-Valent Conjugate Vaccine

We describe the optimization and application of a multiplex bead-based assay (Luminex) to quantify antibodies against polysaccharides of 13 pneumococcal serotypes. In the optimized multiplex immunoassay (MIA), intravenous immune globulin was introduced as an in-house reference serum, and nonspecific...

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Auteurs principaux: Elberse, Karin E. M., Tcherniaeva, Irina, Berbers, Guy A. M., Schouls, Leo M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Vaccine Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849341/
https://ncbi.nlm.nih.gov/pubmed/20130129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00408-09
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