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Prime-Boost Immunization Using a DNA Vaccine Delivered by Attenuated Salmonella enterica Serovar Typhimurium and a Killed Vaccine Completely Protects Chickens from H5N1 Highly Pathogenic Avian Influenza Virus

H5N1 highly pathogenic avian influenza virus (HPAIV) has posed a great threat not only for the poultry industry but also for human health. However, an effective vaccine to provide a full spectrum of protection is lacking in the poultry field. In the current study, a novel prime-boost vaccination str...

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Autors principals: Pan, Zhiming, Zhang, Xiaoming, Geng, Shizhong, Fang, Qiang, You, Meng, Zhang, Lei, Jiao, Xinan, Liu, Xiufan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849337/
https://ncbi.nlm.nih.gov/pubmed/20107004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00387-09
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