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Identification and Analysis of the Biosynthetic Gene Cluster Encoding the Thiopeptide Antibiotic Cyclothiazomycin in Streptomyces hygroscopicus 10-22

Thiopeptide antibiotics are an important class of natural products resulting from posttranslational modifications of ribosomally synthesized peptides. Cyclothiazomycin is a typical thiopeptide antibiotic that has a unique bridged macrocyclic structure derived from an 18-amino-acid structural peptide...

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Detalhes bibliográficos
Main Authors: Wang, Jiang, Yu, Yi, Tang, Kexuan, Liu, Wen, He, Xinyi, Huang, Xi, Deng, Zixin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849233/
https://ncbi.nlm.nih.gov/pubmed/20154110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01790-09
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