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Crowding Effects on Association Reactions at Membranes

The effect of macromolecular crowding on the binding of ligands to a receptor near membranes is studied using Brownian dynamics simulations. The receptor is modeled as a reactive patch on a hard surface and the ligands and crowding agents are modeled as spheres that interact via a steep repulsive in...

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Detalhes bibliográficos
Main Authors: Kim, Jun Soo, Yethiraj, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849078/
https://ncbi.nlm.nih.gov/pubmed/20303852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.022
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