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Understanding the Concentration Dependence of Viral Capsid Assembly Kinetics—the Origin of the Lag Time and Identifying the Critical Nucleus Size

The kinetics for the assembly of viral proteins into a population of capsids can be measured in vitro with size exclusion chromatography or dynamic light scattering, but extracting mechanistic information from these studies is challenging. For example, it is not straightforward to determine the crit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hagan, Michael F., Elrad, Oren M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849049/
https://ncbi.nlm.nih.gov/pubmed/20303864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.023
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