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Plasminogen activator inhibitor type 1 derived peptide, EEIIMD, diminishes cortical infarct but fails to improve neurological function in aged rats following middle cerebral artery occlusion

Age is a primary risk factor in stroke that is often overlooked in animal studies. We contend that using aged animals yields insight into aspects of stroke injury and recovery that are masked, or not elicited, in younger animals. In this study, we examined effects of co-administration of a plasminog...

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Détails bibliographiques
Auteurs principaux: Tan, Zhenjun, Li, Xinlan, Kelly, Kimberly A., Rosen, Charles L., Huber, Jason D.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848998/
https://ncbi.nlm.nih.gov/pubmed/19465008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.05.042
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