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Mice overexpressing corticotropin-releasing factor show brain atrophy and motor dysfunctions
Chronic stress and persistently high glucocorticoid levels can induce brain atrophy. Corticotropin-releasing factor (CRF)-overexpressing (OE) mice are a genetic model of chronic stress with elevated brain CRF and plasma corticosterone levels and Cushing’s syndrome. The brain structural alterations i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848985/ https://ncbi.nlm.nih.gov/pubmed/20132869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.01.068 |
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