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Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346)

BACKGROUND AND PURPOSE: Hydrogen sulphide is an important mediator of gastric mucosal defence. The use of non-steroidal anti-inflammatory drugs continues to be limited by their toxicity, particularly in the upper gastrointestinal tract. We evaluated the gastrointestinal safety and anti-inflammatory...

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Bibliografiset tiedot
Päätekijät: Wallace, John L, Caliendo, Giuseppe, Santagada, Vincenzo, Cirino, Giuseppe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848928/
https://ncbi.nlm.nih.gov/pubmed/20128814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00611.x
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