αII-Spectrin Breakdown Product Cerebrospinal Fluid Exposure Metrics Suggest Differences in Cellular Injury Mechanisms after Severe Traumatic Brain Injury

Traumatic brain injury (TBI) produces αII-spectrin breakdown products (SBDPs) that are potential biomarkers for TBI. To further understand these biomarkers, the present study examined (1) the exposure and kinetic characteristics of SBDPs in cerebrospinal fluid (CSF) of adults with severe TBI, and (2...

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Main Authors: Brophy, Gretchen M., Pineda, Jose A., Papa, Linda, Lewis, Stephen B., Valadka, Alex B., Hannay, H. Julia, Heaton, Shelley C., Demery, Jason A., Liu, Ming Cheng, Tepas, Joseph J., Gabrielli, Andrea, Robicsek, Steven, Wang, Kevin K.W., Robertson, Claudia S., Hayes, Ronald L.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848834/
https://ncbi.nlm.nih.gov/pubmed/19206997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0657
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