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Phosphatidylinositol-3-Kinase/Akt Regulates Bleomycin-Induced Fibroblast Proliferation and Collagen Production

Abnormal repair and dysregulated angiogenesis have been implicated in the pathogenesis of pulmonary fibrosis, but the underlying mechanisms of regulation are not well understood. The present study investigated the role of phosphatidylinositol-3-kinase (PI3K)/Akt in fibrogenesis of human lung fibrobl...

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Detalhes bibliográficos
Main Authors: Lu, Yongju, Azad, Neelam, Wang, Liying, Iyer, Anand K. V., Castranova, Vincent, Jiang, Bing-Hua, Rojanasakul, Yon
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848736/
https://ncbi.nlm.nih.gov/pubmed/19520917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0002OC
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