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Phosphatidylinositol-3-Kinase/Akt Regulates Bleomycin-Induced Fibroblast Proliferation and Collagen Production

Abnormal repair and dysregulated angiogenesis have been implicated in the pathogenesis of pulmonary fibrosis, but the underlying mechanisms of regulation are not well understood. The present study investigated the role of phosphatidylinositol-3-kinase (PI3K)/Akt in fibrogenesis of human lung fibrobl...

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Autors principals: Lu, Yongju, Azad, Neelam, Wang, Liying, Iyer, Anand K. V., Castranova, Vincent, Jiang, Bing-Hua, Rojanasakul, Yon
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848736/
https://ncbi.nlm.nih.gov/pubmed/19520917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0002OC
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