Respiratory Syncytial Virus Impairs Macrophage IFN-α/β– and IFN-γ–Stimulated Transcription by Distinct Mechanisms

Macrophages are the primary lung phagocyte and are instrumental in maintenance of a sterile, noninflamed microenvironment. IFNs are produced in response to bacterial and viral infection, and activate the macrophage to efficiently counteract and remove pathogenic invaders. Respiratory syncytial virus...

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Detalhes bibliográficos
Main Authors: Senft, Albert P., Taylor, Reed H., Lei, Wanli, Campbell, Stephanie A., Tipper, Jennifer L., Martinez, M. Juanita, Witt, Teah L., Clay, Candice C., Harrod, Kevin S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848734/
https://ncbi.nlm.nih.gov/pubmed/19502390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0229OC
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