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A DNA SCISSORS DEVICE USED TO MEASURE MutS BINDING TO DNA MIS-PAIRS
MutS is a DNA repair protein that recognizes unpaired and bulged bases. When it binds to DNA it bends the double helix. We have developed a novel DNA-based nanomechanical device that measures the amount of work that a DNA-bending protein can do when it binds to the double helix. The device we report...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848700/ https://ncbi.nlm.nih.gov/pubmed/20205420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910188p |
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